Growing teratoma syndrome after surgery for ovarian immature teratoma

Growing teratoma syndrome (GTS) is a condition characterized by tumor growth during or after chemotherapy for germ cell tumor, albeit with normal marker levels in the absence of histopathological evidence immature components. We encountered 10-cm large GTS lesion para-aorti nodes fertility-preserving surgery grade 3 ovarian teratoma. The patient was 20 year old woman who presented to hospital complaints abdominal pain and swelling. Imaging examination revealed an mass measuring 24 cm cavity, suspected be composed mixture fat other α-fetoprotein (AFP) were elevated at 853 ng/mL. elected perform surgery. surgical findings included right ovary, which excised without rupture adnexectomy. diagnosis Palpation pelvic para-aortic lymph node areas did not reveal significant lymphadenopathy. Subsequently, metastasis (major axis: 8 cm) discovered before (19 days surgery). confirmed that there no swelling assumed had recurred. Chemotherapy initiated, serum AFP normalized 4 courses bleomycin, etoposide, cisplatin (BEP) therapy. However, grown further 10 cm). Another open performed. nodal completely pathology only mature should considered setting recurrent negative markers.